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Image Search Results
Journal: Nutrients
Article Title: Adiponectin Signaling Modulates Fat Taste Responsiveness in Mice
doi: 10.3390/nu16213704
Figure Lengend Snippet: An AMPK inhibitor (Compound C) eliminates AdipoRon’s ability to enhance LA-induced calcium responses in mouse taste bud cells. The enhancement of taste cell responses to 30 μM LA caused by application of 5 μM AdipoRon was effectively eliminated by the addition of 10 μM Compound C in mouse taste bud cells from ( A ) male circumvallate (F*(2, 51.63) = 10.97, p = 0.0001; W(2, 58.43) = 8.772, p = 0.0005), ( B ) male fungiform (F(2, 105) = 3.562, p = 0.0319), ( C ) female circumvallate (F*(2, 48.23) = 11.35, p < 0.0001; W(2, 60.16) = 6.545, p = 0.0027), and ( D ) female fungiform (F*(2, 137.6) = 8.508, p = 0.0003; W(2, 103.3) = 7.086, p = 0.0013) taste cells. Data are presented as mean ± SEM. One-way ordinary ANOVA with Tukey’s test for multiple comparisons was used to determine statistical significance with equal standard deviations. Brown–Forsythe and Welch ANOVA tests with Dunnett’s T3 multiple comparisons test were introduced when standard deviations significantly differed. The letters above the bars indicate statistically significant groups within each cell type.
Article Snippet: Stock solutions of AdipoRon (MedChem Express, Monmouth Junction, NJ, USA), sulfosuccinimidyl oleate (SSO; Cayman Chemical, Ann Arbor, MI, USA), and
Techniques: